Project A

Participating researchers (PRs): Klaus D. Jandt (FSU), Bettina Löffler (UKJ)

Project description:

Biomaterial implants are frequently used for the treatment of bone injuries or diseases, which can be complicated by biomaterials associated infections (BAIs). These infections are a major clinical challenge, as they are difficult to treat and often require implant replacement.

In our team we aim to develop novel antibiotic-free antimicrobial biomaterials that prevent infections by physical principles on demand and in the long-time course. We aim to develop novel switchable antimicrobial materials that prevent the adhesion of microorganisms and at the same time promote the growth of bone cells. The materials will be tested by in-vitro cultures and in cell culture systems against different microbes, and their virulent behavior will be monitored throughout the microbial contamination process. Furthermore, a potential stimulating effect of the materials on bone cells will be tested for promotion of implant integration.

A materials scientist and a life scientist (microbiology) will work as a tandem team with the PRs on this project.

Doctoral researcher candidates apply for: “A (Materials Science)” or “A (Microbiology)” respectively.